Antitumoral effect of local injection of TLR-9 agonist emulsified in Lipiodol with systemic anti-PD-1 in a murine model of colorectal carcinoma

IntroductionLocal treatments of cancer, including transarterial chemoembolization, could enhance responses to systemic immune checkpoint inhibitors such as anti-PD-1 antibodies. Lipiodol, a radiopaque oil, is widely used for transarterial chemoembolization as a tumor-targeting drug carrier and could...

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Autores principales:	Anne-Laure Grindel, Nathalie Fretellier, Miguel Soares, Nabiha Bouzakher, Vincent Millot Maysounabe, Robin Santus, Olivia Bawa, Melody Wintrebert, Clémence Couquelet, Philippe Robert, Jean-Francois Emile, Claude Capron
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2024-01-01
Colección:	Frontiers in Immunology
Materias:	immunotherapy immunomodulation lipiodol ® preclinical model colorectal carcimoma
Acceso en línea:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1272246/full
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