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hnRNPA2B1 promotes the occurrence and progression of hepatocellular carcinoma by downregulating PCK1 mRNA via a m6A RNA methylation manner

Abstract Background N6-methyladenosine (m6A) is the most prevalent RNA modification. Although hnRNPA2B1, as a reader of m6A modification, has been reported to promote tumorigenesis in a few types of tumors, its role in hepatocellular carcinoma (HCC) and the underlying molecular mechanism remains unc...

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Principais autores: Weijie Hao, Zhimin Chen, Jingzhi Tang, Ru Yang, Wei-Qiang Gao, Huiming Xu
格式: Artigo
语言:Inglês
出版: BMC 2023-11-01
丛编:Journal of Translational Medicine
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在线阅读:https://doi.org/10.1186/s12967-023-04704-4
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