WW Domain-Containing Proteins YAP and TAZ in the Hippo Pathway as Key Regulators in Stemness Maintenance, Tissue Homeostasis, and Tumorigenesis

The Hippo pathway is a conserved signaling pathway originally defined in Drosophila melanogaster two decades ago. Deregulation of the Hippo pathway leads to significant overgrowth in phenotypes and ultimately initiation of tumorigenesis in various tissues. The major WW domain proteins in the Hippo p...

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Bibliografiske detaljer

Principais autores:	Yu-An Chen, Chen-Yu Lu, Tian-You Cheng, Szu-Hua Pan, Hsin-Fu Chen, Nan-Shan Chang
Format:	Artigo
Sprog:	Inglês
Udgivet:	Frontiers Media S.A. 2019-02-01
Serier:	Frontiers in Oncology
Fag:	Hippo pathway WW domain proteins tissue homeostasis regeneration stem cell induced pluripotent stem cells
Online adgang:	https://www.frontiersin.org/article/10.3389/fonc.2019.00060/full
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