Formulation, development and characterization of fosfomycin tromethamine pessaries for the treatment of vaginal infections

Abstract Background The present study investigated the formulation, development, and characterization of Fosfomycin pessaries for the treatment of genitourinary tract infections. To achieve higher local concentration and to avoid the systemic exposure of the body towards Fosfomycin, vaginal pessarie...

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Главные авторы:	Mahboob Ul Haq, Attiqa Naz, Abdul Baseer, Sajjad Ahmad, Basmah F. Alharbi, Muhammad Khurram
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Nature Portfolio 2025-12-01
Серии:	Scientific Reports
Предметы:	Fosfomycin Pessaries Pre-formulation Pharmacokinetics Blood Drug development
Online-ссылка:	https://doi.org/10.1038/s41598-025-29721-9
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