Analysis of sex difference in strychnine-intoxicated rat based on the combination of metabolic kinetics and metabolomics
Abstract Background Drug metabolism va-specific dosing. Strychnine, the primary active compound in strychnine-based alkaloids, is used for treatment of hemiplegia or amblyopia. However, knowledge of sex-based difference in the pharmacokinetics of strychnine remains limited, increasing the risk of do...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BMC
2025-11-01
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| Col·lecció: | Biology of Sex Differences |
| Matèries: | |
| Accés en línia: | https://doi.org/10.1186/s13293-025-00784-7 |
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