Rethinking the network determinants of motor disability in Parkinson’s disease

For roughly the last 30 years, the notion that striatal dopamine (DA) depletion was the critical determinant of network pathophysiology underlying the motor symptoms of Parkinson’s disease (PD) has dominated the field. While the basal ganglia circuit model underpinning this hypothesis has been of gr...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Dalton James Surmeier, Shenyu Zhai, Qiaoling Cui, DeNard V. Simmons
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Frontiers Media S.A. 2023-06-01
Σειρά:	Frontiers in Synaptic Neuroscience
Θέματα:	dopamine basal ganglia circuit Parkinson’s disease plasticity neuromodulation
Διαθέσιμο Online:	https://www.frontiersin.org/articles/10.3389/fnsyn.2023.1186484/full
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