Inter-tumor genomic heterogeneity of breast cancers: comprehensive genomic profile of primary early breast cancers and relapses

Abstract Background The breast cancer genome dynamically evolves during malignant progression and recurrence. We investigated the genomic profiles of primary early-stage breast cancers and matched relapses to elucidate the molecular underpinnings of the metastatic process, focusing on potentially ac...

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Principais autores:	Caterina Fumagalli, Alberto Ranghiero, Sara Gandini, Federica Corso, Sergio Taormina, Elisa De Camilli, Alessandra Rappa, Davide Vacirca, Giuseppe Viale, Elena Guerini-Rocco, Massimo Barberis
格式:	Artigo
语言:	Inglês
出版:	BMC 2020-10-01
丛编:	Breast Cancer Research
主题:	Breast cancer Recurrence Genomic heterogeneity TP53 MYC Next-generation sequencing
在线阅读:	http://link.springer.com/article/10.1186/s13058-020-01345-z
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