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An RNA Metabolism and Surveillance Quartet in the Major Histocompatibility Complex

At the central region of the mammalian major histocompatibility complex (MHC) is a complement gene cluster that codes for constituents of complement C3 convertases (C2, factor B and C4). Complement activation drives the humoral effector functions for immune response. Sandwiched between the genes for...

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Principais autores: Danlei Zhou, Michalea Lai, Aiqin Luo, Chack-Yung Yu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2019-08-01
coleção:Cells
Assuntos:
DXO
DOM3Z
NELF-E
RD
SKIV2L
SKI2W
STK19
RP1
NSDK
RLR
miR1236
SVA
RNA quality control
5′→3′ RNA decay
3′→5′ mRNA turnover
antiviral immunity
interferon β
promoter-proximal transcriptional pause
exosomes
nuclear kinase
hepatocellular carcinoma
Ski complex
trichohepatoenteric syndrome
melanoma
Acesso em linha:https://www.mdpi.com/2073-4409/8/9/1008
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