Comprehensive single-cell analysis reveals cellular heterogeneity and immune interactions in colorectal cancer

Colorectal cancer (CRC) presents considerable therapeutic challenges due to its diverse cellular composition and intricate microenvironment. Our study utilized single-cell RNA sequencing (scRNA-seq) on CRC tissues, examining 18,741 individual cells, which were grouped into six primary cell populatio...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Zhenyu Chi, Rui Kong, Song Wang, Shaofan Qiu
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2026-06-01
Schriftenreihe:	Translational Oncology
Schlagworte:	Colorectal cancer Single-cell RNA sequencing Tumor microenvironment Immune cell subtypes Prognostic biomarkers
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S1936523326000987
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