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Single-cell characterization and quantification of translation-competent viral reservoirs in treated and untreated HIV infection.

The phenotypic characterization of the cells in which HIV persists during antiretroviral therapy (ART) remains technically challenging. We developed a simple flow cytometry-based assay to quantify and characterize infected cells producing HIV proteins during untreated and treated HIV infection. By c...

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Bibliografiske detaljer
Principais autores: Marion Pardons, Amy E Baxter, Marta Massanella, Amélie Pagliuzza, Rémi Fromentin, Caroline Dufour, Louise Leyre, Jean-Pierre Routy, Daniel E Kaufmann, Nicolas Chomont
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2019-02-01
Serier:PLoS Pathogens
Online adgang:https://doi.org/10.1371/journal.ppat.1007619
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