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Biotinylated Bilirubin Nanoparticles as a Tumor Microenvironment‐Responsive Drug Delivery System for Targeted Cancer Therapy

Abstract The tumor microenvironment (TME) plays a crucial role in tumorigenesis and cancer cell metastasis. Accordingly, a drug‐delivery system (DDS) that is capable of targeting tumor and releasing drugs in response to TME‐associated stimuli should lead to potent antitumor efficacy. Here, a cancer...

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Principais autores: Yonghyun Lee, Soyoung Lee, Sangyong Jon
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2018-06-01
Serier:Advanced Science
Fag:
bilirubin nanoparticles
biotin transporters
reactive oxygen species (ROS)
stimuli responsiveness
targeted cancer therapy
tumor microenvironments
Online adgang:https://doi.org/10.1002/advs.201800017
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