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HIV-2 neutralization by intact V3-specific Fab fragments

<p>Abstract</p> <p>The V3 region of both HIV-1 gp120 and HIV-2 gp125 surface glycoprotein has been described as a target for neutralizing antibodies. In this study a conformation-sensitive (3C4) and a linear site-specific (7C8) anti-HIV-2 V3 monoclonal antibody (mAb) were characterized. The neutrali...

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Bibliographic Details
Main Authors: Sourial Samer, Nilsson Charlotta
Format: Artigo
Language:Inglês
Published: BMC 2008-08-01
Series:Virology Journal
Online Access:http://www.virologyj.com/content/5/1/96
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