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Renometabolic disorder in experimental rat model of polycystic ovarian syndrome is reversed by acetate-mediated inhibition of pyruvate dehydrogenase kinase 4

Abstract Background Chronic Kidney disorders is a global public health problem, including in women with polycystic ovarian syndrome (PCOS), and is characterized by renal fibrosis, nephrotoxicity and glomerulonephritis, which increases the possibility of renal failure and organ transplant. Pyruvate d...

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Váldodahkkit: Stephanie E. Areloegbe, Chukwubueze L. Atuma, Ayodeji Aturamu, Isaac O. Ajadi, Oluseyi E. Adelekan, Mary B. Ajadi, Christopher O. Akintayo, Gloria O. Omoruyi, Samuel O. Onyekweli, Omosola F. Anifowose, Oluwatobi A. Amusa, Kayode Ajayi, Paul A. Oyewole, Tolulope E. Adegoke, Kehinde S. Olaniyi
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: BMC 2025-05-01
Ráidu:BMC Nephrology
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Liŋkkat:https://doi.org/10.1186/s12882-025-04157-5
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