Pharmacokinetics and metabolism of artemisinin (ART) in Plasmodium yoelii: ART-heme adduct as a potential biomarker for its resistance
Background: Plasmodium falciparum in Southeast Asia and Africa is developing resistance to the antimalarial drug artemisinin (ART). In this study, the metabolite of ART in P. yoelii parasites was evaluated as a potential biomarker for its antimalarial activity as well as its resistance. Methods: The...
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| Glavni autori: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Elsevier
2025-08-01
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| Serija: | International Journal for Parasitology: Drugs and Drug Resistance |
| Teme: | |
| Online pristup: | http://www.sciencedirect.com/science/article/pii/S2211320725000260 |
| Oznake: |
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