New Amino Naphthoquinone Derivatives as Anti-<i>Trypanosoma cruzi</i> Agents Targeting Trypanothione Reductase

To develop novel chemotherapeutic alternatives for the treatment of Chagas disease, in this study, a set of new amino naphthoquinone derivatives were synthesised and evaluated in vitro on the epimastigote and trypomastigote forms of <i>Trypanosoma cruzi</i> strains (NINOA and INC-5) and on J774 muri...

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主要な著者:	Christian Espinosa-Bustos, Mariana Ortiz Pérez, Alonzo Gonzalez-Gonzalez, Ana María Zarate, Gildardo Rivera, Javier A. Belmont-Díaz, Emma Saavedra, Mauricio A. Cuellar, Karina Vázquez, Cristian O. Salas
フォーマット:	Artigo
言語:	Inglês
出版事項:	MDPI AG 2022-05-01
シリーズ:	Pharmaceutics
主題:	<i>Trypanosoma cruzi</i> amino naphthoquinones trypomastigote epimastigote trypanothione reductase docking studies
オンライン･アクセス:	https://www.mdpi.com/1999-4923/14/6/1121
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