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Cancer and lymphatic marker FOXC2 drives wound healing and fibrotic tissue formation

IntroductionThe FOXC2 transcription factor has been tied to a wide range of disease states, serving as a promising prognostic biomarker associated with aggressive basal-like human breast cancers (increased cancer invasion and metastasis). Dysregulation of FOXC2 expression has also been found to prom...

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Autors principals: Maia B. Granoski, Katharina S. Fischer, William W. Hahn, Dharshan Sivaraj, Hudson C. Kussie, Filiberto Quintero, Abdelrahman M. Alsharif, Eamonn McKenna, Jonathan P. Yasmeh, Andrew C. Hostler, Maria Gracia Mora Pinos, Robert P. Erickson, Marlys H. Witte, Kellen Chen, Geoffrey C. Gurtner
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2024-10-01
Col·lecció:Frontiers in Physiology
Matèries:
FOXC2
lymphatics
wound healing
inflammation
fibrosis
Accés en línia:https://www.frontiersin.org/articles/10.3389/fphys.2024.1427113/full
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