An overlooked phenomenon: complex interactions of potential error sources on the quality of bacterial de novo genome assemblies

Abstract Background Parameters adversely affecting the contiguity and accuracy of the assemblies from Illumina next-generation sequencing (NGS) are well described. However, past studies generally focused on their additive effects, overlooking their potential interactions possibly exacerbating one an...

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Autors principals:	Zoltán Rádai, Alex Váradi, Péter Takács, Nikoletta Andrea Nagy, Nicholas Schmitt, Eszter Prépost, Gábor Kardos, Levente Laczkó
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2024-01-01
Col·lecció:	BMC Genomics
Matèries:	Sequencing error Sequencing depth PCR duplicates Optical duplicates Bacterial genomes
Accés en línia:	https://doi.org/10.1186/s12864-023-09910-4
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