Selective ablation of Ctip2/Bcl11b in epidermal keratinocytes triggers atopic dermatitis-like skin inflammatory responses in adult mice.

Ctip2 is crucial for epidermal homeostasis and protective barrier formation in developing mouse embryos. Selective ablation of Ctip2 in epidermis leads to increased transepidermal water loss (TEWL), impaired epidermal proliferation, terminal differentiation, as well as altered lipid composition duri...

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Detalhes bibliográficos

Principais autores:	Zhixing Wang, Ling-Juan Zhang, Gunjan Guha, Shan Li, Kateryna Kyrylkova, Chrissa Kioussi, Mark Leid, Gitali Ganguli-Indra, Arup K Indra
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2012-01-01
coleção:	PLoS ONE
Acesso em linha:	http://europepmc.org/articles/PMC3527437?pdf=render
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