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The Human Myofibroblast Marker Xylosyltransferase-I: A New Indicator for Macrophage Polarization

Chronic inflammation and excessive synthesis of extracellular matrix components, such as proteoglycans (PG), by fibroblast- or macrophage-derived myofibroblasts are the hallmarks of fibrotic diseases, including systemic sclerosis (SSc). Human xylosyltransferase-I (XT-I), which is encoded by the gene...

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Principais autores: Thanh-Diep Ly, Monika Wolny, Christopher Lindenkamp, Ingvild Birschmann, Doris Hendig, Cornelius Knabbe, Isabel Faust-Hinse
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2022-11-01
coleção:Biomedicines
Assuntos:
cytokines
fibrosis
inflammation
macrophage
proteoglycan
systemic sclerosis
Acesso em linha:https://www.mdpi.com/2227-9059/10/11/2869
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