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GSK2334470 attenuates high salt-exacerbated rheumatoid arthritis progression by restoring Th17/Treg homeostasis

Summary: High salt (HS) consumption is a risk factor for multiple autoimmune disorders via disturbing immune homeostasis. Nevertheless, the exact mechanisms by which HS exacerbates rheumatoid arthritis (RA) pathogenesis remain poorly defined. Herein, we found that heightened phosphorylation of PDPK1...

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Principais autores: Qian Mo, Mansoor Bolideei, Shan-Jie Rong, Jia-Hui Luo, Chun-Liang Yang, Wan-Ying Lu, Qi-Jie Chen, Jia-Wei Zhao, Fa-Xi Wang, Ting Wang, Yang Li, Xi Luo, Shu Zhang, Fei Xiong, Qi-Lin Yu, Zi-Yun Zhang, Shi-Wei Liu, Fei Sun, Ling-Li Dong, Cong-Yi Wang
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2024-06-01
coleção:iScience
Assuntos:
Pharmacology
Natural sciences
Biological sciences
Physiology
Immunology
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2589004224010204
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