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Synergistic potential of Leu10-teixobactin and cefepime against multidrug-resistant Staphylococcus aureus

Abstract Staphylococcus aureus (S. aureus) is a significant Gram-positive opportunistic pathogen behind many debilitating infections. β-lactam antibiotics are conventionally prescribed for treating S. aureus infections. However, the adaptability of S. aureus in evolving resistance to multiple β-lact...

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Principais autores: Augustine Jing Jie Koh, Maytham Hussein, Varsha Thombare, Simon Crawford, Jian Li, Tony Velkov
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2024-10-01
Serier:BMC Microbiology
Fag:
Leu10-teixobactin
Cefepime
Methicillin-resistant Staphylococcus aureus (MRSA)
Synergistic activity
Biofilm inhibition
β-lactam potentiation
Online adgang:https://doi.org/10.1186/s12866-024-03577-x
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