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The pharmacological impact of ATP-binding cassette drug transporters on vemurafenib-based therapy

Melanoma is the most serious type of skin cancer and one of the most common cancers in the world. Advanced melanoma is often resistant to conventional therapies and has high potential for metastasis and low survival rates. Vemurafenib is a small molecule inhibitor of the BRAF serine-threonine kinase...

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Bibliografische gegevens
Hoofdauteurs: Chung-Pu Wu, Suresh V. Ambudkar
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2014-04-01
Reeks:Acta Pharmaceutica Sinica B
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Online toegang:http://www.sciencedirect.com/science/article/pii/S2211383513001068
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