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The composition and organization of Drosophila heterochromatin are heterogeneous and dynamic

Heterochromatin is enriched for specific epigenetic factors including Heterochromatin Protein 1a (HP1a), and is essential for many organismal functions. To elucidate heterochromatin organization and regulation, we purified Drosophila melanogaster HP1a interactors, and performed a genome-wide RNAi sc...

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Principais autores: Joel M Swenson, Serafin U Colmenares, Amy R Strom, Sylvain V Costes, Gary H Karpen
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications Ltd 2016-08-01
Serier:eLife
Fag:
heterochromatin
cell biology
genome-wide RNAi screen
nuclear organization
position effect variegation
Online adgang:https://elifesciences.org/articles/16096
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