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Introns regulate gene expression in Cryptococcus neoformans in a Pab2p dependent pathway.

Most Cryptococccus neoformans genes are interrupted by introns, and alternative splicing occurs very often. In this study, we examined the influence of introns on C. neoformans gene expression. For most tested genes, elimination of introns greatly reduces mRNA accumulation. Strikingly, the number an...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Carolin Goebels, Aline Thonn, Sara Gonzalez-Hilarion, Olga Rolland, Frederique Moyrand, Traude H Beilharz, Guilhem Janbon
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2013-01-01
Schriftenreihe:PLoS Genetics
Online-Zugang:http://europepmc.org/articles/PMC3744415?pdf=render
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