Nanolipoprotein particle (NLP) vaccine confers protection against Yersinia pestis aerosol challenge in a BALB/c mouse model

IntroductionYersinia pestis is the etiological agent of plague, a disease that remains a concern as demonstrated by recent outbreaks in Madagascar. Infection with Y. pestis results in a rapidly progressing illness that can only be successfully treated with antibiotics given shortly after symptom ons...

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Hlavní autoři:	Sergei S. Biryukov, Amy Rasley, Michael L. Davies, Christopher P. Klimko, Jennifer L. Dankmeyer, Melissa Hunter, Nathaniel O. Rill, Jennifer L. Shoe, Jeremy Miller, Yuli Talyansky, Barbara Sullinger, Matheo Herrera, Daniel Huang, Leslie Bautista, Lucy Pepe, Sandra K. G. Peters, Christian J. Xander, Elsie E. Martinez, Ronald G. Toothman, Kevin D. Mlynek, Joel A. Bozue, Ju Qiu, Nicholas O. Fischer, Christopher K. Cote
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2025-06-01
Edice:	Frontiers in Immunology
Témata:	plague Yersinia pestis vaccine nanolipoprotein particle mice pneumonic
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1603710/full
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