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Global chromatin conformation differences in the Drosophila dosage compensated chromosome X

In Drosophila, dosage compensation involves a twofold transcriptional upregulation of the single male chromosome X. Here the authors show that global conformational differences are specifically present in the male X chromosome and detectable using Hi-C data, indicating that dosage compensation affec...

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主要な著者: Koustav Pal, Mattia Forcato, Daniel Jost, Thomas Sexton, Cédric Vaillant, Elisa Salviato, Emilia Maria Cristina Mazza, Enrico Lugli, Giacomo Cavalli, Francesco Ferrari
フォーマット: Artigo
言語:Inglês
出版事項: Nature Portfolio 2019-11-01
シリーズ:Nature Communications
オンライン・アクセス:https://doi.org/10.1038/s41467-019-13350-8
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