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Deguelin inhibits the proliferation of human multiple myeloma cells by inducing apoptosis and G2/M cell cycle arrest: Involvement of Akt and p38 MAPK signalling pathway

Deguelin exhibits antiproliferative activity against various cancer cell types. Previous studies have reported that deguelin exhibits pro-apoptotic activity against human cancer cells. The current study aimed at further elaborating the anticancer effects of deguelin against multiple myeloma cells. C...

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Principais autores: Sun Kening, Chen Ping, Zhang Liang, Lu Zhidong, Jin Qunhua
Formato: Artigo
Idioma:Inglês
Publicado em: Sciendo 2024-03-01
coleção:Acta Pharmaceutica
Assuntos:
multiple myeloma
deguelin
apoptosis
g2/m cell cycle arrest
metastasis
p38 mapk signalling pathway
Acesso em linha:https://doi.org/10.2478/acph-2024-0003
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