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Impact of the Gastric Acid Suppressant Use on the Safety and Effectiveness of EGFR-TKIs: A Systematic Review and Meta-Analysis

Background The use of gastric acid suppressants (GASs) has an influence on the exposure of some epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) and therefore may affect the effectiveness and safety of EGFR-TKIs. The impact of GASs, including proton pump inhibitors (PPIs) and...

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Bibliografische Detailangaben
Hauptverfasser: Xin Du, Wei Liu, Ken Chen, Ziyu Wang, Xinyi Li, Li Yang, Xiaohui Xie
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2022-06-01
Schriftenreihe:Frontiers in Pharmacology
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Online-Zugang:https://www.frontiersin.org/articles/10.3389/fphar.2022.796538/full
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