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Pax transactivation domain-interacting protein is required for preserving hematopoietic stem cell quiescence via regulating lysosomal activity

Hematopoietic stem cells (HSC) maintain lifetime whole blood hematopoiesis through self-renewal and differentiation. In order to sustain HSC stemness, most HSC reside in a quiescence state, which is affected by diverse cellular stress and intracellular signal transduction. How HSC accommodate those...

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Hlavní autoři: Tong Zhang, Manman Cui, Yashu Li, Ying Cheng, Zhuying Gao, Jing Wang, Tiantian Zhang, Guoqiang Han, Rong Yin, Peipei Wang, Wen Tian, Weidong Liu, Jin Hu, Yuhua Wang, Zheming Liu, Haojian Zhang
Médium: Artigo
Jazyk:Inglês
Vydáno: Ferrata Storti Foundation 2023-03-01
Edice:Haematologica
On-line přístup:https://haematologica.org/article/view/11018
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