Development and validation of basement membrane-related signatures for predicting postoperative recurrence, tumor microenvironment and drug candidates in chordomas

Abstract Background Skull base chordoma is a rare and aggressive bone tumor with a poor prognosis. The basement membrane (BM) plays an pivotal role in tumor progression. However, the involvement of BM-related genes in assessing the prognosis and influencing the biological behavior of skull base chor...

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Detalhes bibliográficos

Principais autores:	Tianhao Zhang, Mingxuan Li, Xing Liu, Sida Zhao, Tianshun Ma, Yide Liu, Xijia Zhang, Qian Liu, Jiwei Bai, Yazhuo Zhang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-04-01
coleção:	BMC Cancer
Assuntos:	Skull base Chordoma Base membrane Prognostic Immune Drug sensitivity PI3K-Akt signaling pathway
Acesso em linha:	https://doi.org/10.1186/s12885-025-14006-1
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