Icariin regulates miR-23a-3p-mediated osteogenic differentiation of BMSCs via BMP-2/Smad5/Runx2 and WNT/β-catenin pathways in osteonecrosis of the femoral head

Icariin is commonly used for the clinical treatment of osteonecrosis of the femoral head (ONFH). miR-23a-3p plays a vital role in regulating the osteogenic differentiation of bone marrow-derived mesenchymal stem cells (BMSCs). The present study aimed to investigate the roles of icariin and miR-23a-3...

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Autors principals:	Xiao-yun Zhang, Hua-nan Li, Feng Chen, Yue-ping Chen, Yuan Chai, Jian-zhao Liao, Bin Gan, Ding-peng Chen, Song Li, Yong-qian Liu
Format:	Artigo
Idioma:	Inglês
Publicat:	Springer 2021-12-01
Col·lecció:	Saudi Pharmaceutical Journal
Matèries:	Icariin miR-23a-3p Osteonecrosis of the femoral head BMP-2/Smad5/Runx2 pathway WNT/β-catenin pathway
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S1319016421002115
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