Rutin alleviates ventilator-induced lung injury by inhibiting NLRP3 inflammasome activation

Summary: Whether rutin relieves ventilator-induced lung injury (VILI) remains unclear. Here, we used network pharmacology, bioinformatics, and molecular docking to predict the therapeutic targets and potential mechanisms of rutin in the treatment of VILI. Subsequently, a mouse model of VILI was esta...

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Bibliografische Detailangaben

Hauptverfasser:	Shengsong Chen, Yu Bai, Jingen Xia, Yi Zhang, Qingyuan Zhan
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2023-10-01
Schriftenreihe:	iScience
Schlagworte:	Cell biology Immunology Molecular biology
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S2589004223019430
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