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The safety profiles of avacopan on microscopic polyangiitis and granulomatosis with polyangiitis: a real-world pharmacovigilance analysis

BackgroundAvacopan is an oral selective C5a receptor inhibitor. It received FDA approval in October 2021 for use with standard glucocorticoid therapy to treat antineutrophil cytoplasmic antibody-associated vasculitis. However, there are limitations to understanding adverse events (AEs) in clinical p...

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Autors principals: Yang Li, Anna Meng, Yue Wang
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2025-10-01
Col·lecció:Frontiers in Immunology
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Accés en línia:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1654735/full
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