Distinct Phenotypes Caused by Mutation of MSH2 in Trypanosome Insect and Mammalian Life Cycle Forms Are Associated with Parasite Adaptation to Oxidative Stress.

<h4>Background</h4>DNA repair mechanisms are crucial for maintenance of the genome in all organisms, including parasites where successful infection is dependent both on genomic stability and sequence variation. MSH2 is an early acting, central component of the Mismatch Repair (MMR) pathway, which is...

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التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Viviane Grazielle-Silva, Tehseen Fatima Zeb, Jason Bolderson, Priscila C Campos, Julia B Miranda, Ceres L Alves, Carlos R Machado, Richard McCulloch, Santuza M R Teixeira
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	Public Library of Science (PLoS) 2015-06-01
سلاسل:	PLoS Neglected Tropical Diseases
الوصول للمادة أونلاين:	https://doi.org/10.1371/journal.pntd.0003870
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!