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Chrysophanol inhibits of colorectal cancer cell motility and energy metabolism by targeting the KITENIN/ErbB4 oncogenic complex

Abstract Background Expression of the KITENIN/ErbB4 oncogenic complex is associated with metastasis of colorectal cancer to distant organs and lymph nodes and is linked with poor prognosis and poor survival. Methods Here, we used in vitro and in silico methods to test the ability of chrysophanol, a...

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Detalles Bibliográficos
Principais autores: Mücahit Varlı, Eunae Kim, Songjin Oh, Sultan Pulat, Rui Zhou, Chathurika D. B. Gamage, Barış Gökalsın, Nüzhet Cenk Sesal, Kyung Keun Kim, Man-Jeong Paik, Hangun Kim
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2024-07-01
Series:Cancer Cell International
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Acceso en liña:https://doi.org/10.1186/s12935-024-03434-x
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