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p32-Dependent p38 MAPK Activation by Arginase II Downregulation Contributes to Endothelial Nitric Oxide Synthase Activation in HUVECs

Arginase II reciprocally regulates endothelial nitric oxide synthase (eNOS) through a p32-dependent Ca<sup>2+</sup> control. We investigated the signaling pathway of arginase II-dependent eNOS phosphorylation. Western blot analysis was applied for examining protein activation and [Ca<sup>2+</sup>]c...

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Principais autores: Bon-Hyeock Koo, Moo-Ho Won, Young-Myeong Kim, Sungwoo Ryoo
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2020-02-01
Serier:Cells
Fag:
arginase ii
calcium
endothelial nitric oxide synthase
p38 mapk
p32
Online adgang:https://www.mdpi.com/2073-4409/9/2/392
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