Complement-Mediated Differential Immune Response of Human Macrophages to Sporothrix Species Through Interaction With Their Cell Wall Peptidorhamnomannans

In this study, the human immune response mechanisms against Sporothrix brasiliensis and Sporothrix schenckii, two causative agents of human and animal sporotrichosis, were investigated. The interaction of S. brasiliensis and S. schenckii with human monocyte-derived macrophages (hMDMs) was shown to b...

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Autori principali:	Gabriela W. P. Neves, Sarah Sze Wah Wong, Vishukumar Aimanianda, Catherine Simenel, J. Iñaki Guijarro, Catriona Walls, Janet A. Willment, Neil A. R. Gow, Carol A. Munro, Gordon D. Brown, Leila M. Lopes-Bezerra
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2021-11-01
Serie:	Frontiers in Immunology
Soggetti:	Sporothrix schenckii Sporothrix brasiliensis complement receptor-3 (CR3) cell wall peptidorhamnomannan (PRM) human macrophages
Accesso online:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.749074/full
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