Modulation of Kinase Activities In Vitro by Hepatitis C Virus Protease NS3/NS4A Mediated-Cleavage of Key Immune Modulator Kinases

Hepatitis C Virus NS3/NS4A, a serine protease complex, has been found to interact with many host proteins and cause various adverse effects on cellular function and immune response. For example, the cleavage of important immune factors by NS3/NS4A has been suggested as a mechanism for the hepatitis...

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Principais autores:	Mohd Amir F. Abdullah, Sarah M. McWhirter, Zucai Suo
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2023-01-01
coleção:	Cells
Assuntos:	IKKα, IKKβ, IKKε, TBK1 HCV protease kinase regulatory domain
Acesso em linha:	https://www.mdpi.com/2073-4409/12/3/406
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