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Transcription factor-based classification of pituitary adenomas / PitNETs: a comparative analysis and clinical implications across WHO 2004, 2017 and 2022 in 921 cases

Abstract The WHO classifications of 2017 and 2022 recommend the use of pituitary transcription factors PIT-1, T-PIT and SF-1 as well as GATA3 and ERα for histopathological diagnosis. The aim of this study is to demonstrate their diagnostic impact in a large retrospective cohort. 921 PitNETs/PAs diag...

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Principais autores: Isabella Nasi-Kordhishti, Mirko Hladik, Kosmas Kandilaris, Felix Behling, Jürgen Honegger, Jens Schittenhelm
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2025-06-01
coleção:Acta Neuropathologica Communications
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Acesso em linha:https://doi.org/10.1186/s40478-025-02050-8
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