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Integrated molecular subtyping and functional analysis of circ_0001946/miR-7-5p axis reveals a glucose metabolism-linked regulatory mechanism in ovarian cancer

Abstract Background Ovarian cancer (OvCa) remains one of the most lethal gynecological malignancies, primarily due to late-stage diagnosis, chemoresistance, and substantial molecular heterogeneity. Emerging evidence highlights the pivotal roles of microRNAs (miRNAs) and circular RNAs (circRNAs) in t...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Yanlei Dong, Guiyu Zhang
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2025-12-01
Schriftenreihe:World Journal of Surgical Oncology
Schlagworte:
Ovarian cancer
Micro RNAs
Hsa-miR-7-5p
Circ_0001946
Glucose metabolism
OVCAR3
Online-Zugang:https://doi.org/10.1186/s12957-025-04140-2
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