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In vivo T cell activation in lymphoid tissues is inhibited in the oxygen-poor microenvironment

Activation of immune cells is under control of immunological and physiological regulatory mechanisms to ensure adequate destruction of pathogens with the minimum collateral damage to innocent bystander cells. The concept of physiological negative regulation of immune response has been advocated bas...

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Auteurs principaux: Akio eOhta, Rohan eDiwanji, Radhika eKini, Meenakshi eSubramanian, Akiko eOhta, Michail eSitkovsky
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2011-07-01
Collection:Frontiers in Immunology
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Accès en ligne:http://journal.frontiersin.org/Journal/10.3389/fimmu.2011.00027/full
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