Synthesis, Molecular Docking, Druglikeness Analysis, and ADMET Prediction of the Chlorinated Ethanoanthracene Derivatives as Possible Antidepressant Agents

Ethanoanthracene cycloadducts <b>(5–7) <i>anti</i>, (5–7) <i>syn</i>,</b> and <b>(5–7) <i>dec</i></b> have been synthesized from the Diels–Alder (DA) reaction of diene 1,8-dichloroanthracene <b>2</b>, with the dienophiles; acrylonitrile <b>3</b>, 1-cynavinyl acetate <b>4,</b> and phenyl vinyl sulfon...

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Principais autores:	Mujeeb A. Sultan, Mansour S. A. Galil, Mohyeddine Al-Qubati, Mufeed M. Omar, Assem Barakat
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2020-10-01
Series:	Applied Sciences
Assuntos:	anthracenes Diels-Alder ADMET prediction pharmacokinetic druglikeness antidepressant
Acceso en liña:	https://www.mdpi.com/2076-3417/10/21/7727
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