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Regulation of Zfp36 by ISGF3 and MK2 restricts the expression of inflammatory cytokines during necroptosis stimulation

Abstract Necrosome activation following TLR- or cytokine receptor-signaling results in cell death by necroptosis which is characterized by the rupture of cell membranes and the consequent release of intracellular contents to the extracellular milieu. While necroptosis exacerbates various inflammator...

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Principais autores: Sahil Yadav, Rayan El Hamra, Norah A. Alturki, Ardeshir Ariana, Avni Bhan, Kate Hurley, Matthias Gaestel, Perry J. Blackshear, Alexandre Blais, Subash Sad
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2024-08-01
coleção:Cell Death and Disease
Acesso em linha:https://doi.org/10.1038/s41419-024-06964-4
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