Persistent high glucose induced EPB41L4A‐AS1 inhibits glucose uptake via GCN5 mediating crotonylation and acetylation of histones and non‐histones

Abstract Background Persistent hyperglycemia decreases the sensitivity of insulin‐sensitive organs to insulin, owing to which cells fail to take up and utilize glucose, which exacerbates the progression of type 2 diabetes mellitus (T2DM). lncRNAs' abnormal expression is reported to be associated wit...

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Hlavní autoři:	Weijie Liao, Naihan Xu, Haowei Zhang, Weifang Liao, Yanzhi Wang, Songmao Wang, Shikuan Zhang, Yuyang Jiang, Weidong Xie, Yaou Zhang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Wiley 2022-02-01
Edice:	Clinical and Translational Medicine
Témata:	acetylation crotonylation EPB41L4A‐AS1 GCN5 T2DM
On-line přístup:	https://doi.org/10.1002/ctm2.699
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