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Modeling and predicting the overlap of B- and T-cell receptor repertoires in healthy and SARS-CoV-2 infected individuals.

Adaptive immunity's success relies on the extraordinary diversity of protein receptors on B and T cell membranes. Despite this diversity, the existence of public receptors shared by many individuals gives hope for developing population-wide vaccines and therapeutics. Using probabilistic modeling, we...

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Hlavní autoři: María Ruiz Ortega, Natanael Spisak, Thierry Mora, Aleksandra M Walczak
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2023-02-01
Edice:PLoS Genetics
On-line přístup:https://doi.org/10.1371/journal.pgen.1010652
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