A luteinizing hormone receptor intronic variant is significantly associated with decreased risk of Alzheimer's disease in males carrying an apolipoprotein E ε4 allele

<p>Abstract</p> <p>Genetic and biochemical studies support the apolipoprotein E (<it>APOE</it>) ε4 allele as a major risk factor for late-onset Alzheimer's disease (AD), though ~50% of AD patients do not carry the allele. APOE transports cholesterol for luteinizing hormone (LH)-regulated steroidogen...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Gleason Carey E, Meethal Sivan, Ahmadi M Reza, Haasl Ryan J, Johnson Sterling C, Asthana Sanjay, Bowen Richard L, Atwood Craig S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2008-04-01
coleção:	BMC Medical Genetics
Acesso em linha:	http://www.biomedcentral.com/1471-2350/9/37
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!