Signal Amplification in Highly Ordered Networks Is Driven by Geometry

Here, we hypothesize that, in biological systems such as cell surface receptors that relay external signals, clustering leads to substantial improvements in signaling efficiency. Representing cooperative signaling networks as planar graphs and applying Euler’s polyhedron formula, we can show that cl...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Éva S. Vanamee, Gábor Lippner, Denise L. Faustman
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	MDPI AG 2022-01-01
Sarja:	Cells
Aiheet:	TNF superfamily signaling hexagonal clustering Euler polyhedron formula
Linkit:	https://www.mdpi.com/2073-4409/11/2/272
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