In vivo detection of tau fibrils and amyloid β aggregates with luminescent conjugated oligothiophenes and multiphoton microscopy

Summary The detection of amyloid beta deposits and neurofibrillary tangles, both hallmarks of Alzheimer’s disease (AD), is key to understanding the mechanisms underlying these pathologies. Luminescent conjugated oligothiophenes (LCOs) enable fluorescence imaging of these protein aggregates. Using LC...

पूर्ण विवरण

ग्रंथसूची विवरण

मुख्य लेखकों:	Maria Calvo-Rodriguez, Steven S. Hou, Austin C. Snyder, Simon Dujardin, Hamid Shirani, K. Peter R. Nilsson, Brian J. Bacskai
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	BMC 2019-11-01
श्रृंखला:	Acta Neuropathologica Communications
विषय:	Alzheimer’s disease Amyloid beta plaques Cerebral amyloid angiopathy Luminescence Multiphoton microscopy Neurofibrillary tangles
ऑनलाइन पहुंच:	http://link.springer.com/article/10.1186/s40478-019-0832-1
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