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Mutational analysis of human norovirus VP2 elucidates critical molecular interactions for virus assembly

ABSTRACT Human noroviruses (HuNoVs) are the leading cause of viral gastroenteritis, with ≥80% of infections caused by the GII genogroup. HuNoVs are non-enveloped, with an icosahedral capsid composed of 90 dimers of the major capsid protein VP1, which encloses a minor structural protein, VP2, and a V...

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Autori principali: Janam J. Dave, Sue E. Crawford, Robert L. Atmar, Khalil Ettayebi, B. V. Venkataram Prasad, Mary K. Estes
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2026-02-01
Serie:Journal of Virology
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Accesso online:https://journals.asm.org/doi/10.1128/jvi.01420-25
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