Neutrophil elastase downmodulates native G-CSFR expression and granulocyte-macrophage colony formation
<p>Abstract</p> <p>Background</p> <p>The granulocyte colony-stimulating factor receptor (G-CSFR) plays a critical role in maintaining homeostatic levels of circulating neutrophils (PMN). The mechanisms modulating G-CSFR surface expression to prevent chronic neutrophilia are poorly understood. Here,...
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| Principais autores: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2010-01-01
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| coleção: | Journal of Inflammation |
| Acesso em linha: | http://www.journal-inflammation.com/content/7/1/5 |
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